CD 56 – Serum Therapy

Pregnancies at 35 years of age or older are called late-term pregnancies. Fertility begins to decline in women in their 30s and continues to decline at an accelerated rate after their 40s. The reason for the decline in fertility is that women have a certain number of eggs when they are born and this number decreases over time. The decrease in the potential of the ovaries to produce eggs results in a decrease in pregnancy rates, both naturally and through treatments.

Another important aspect of pregnancy at older ages is the decline in egg quality. According to statistics on this subject; the rate of achieving a pregnancy resulting in a live birth within 1 year is 75% in 30-year-old patients, 66% in 35-year-olds and 44% in 40-year-olds. In addition, in advanced age pregnancies with egg aging, there is a high chance that the pregnancy will end in miscarriage. Gynecological problems such as fibroids and medical problems such as diabetes and goiter are also common with advanced age.

These cells, known as natural killer (NK) cells, whose numbers in the uterus are altered for different reasons, have a negative effect on the occurrence of pregnancy. The CD 56 test is a test that detects the density of these cells in the lining of the uterus. In spontaneous pregnancies or pregnancies achieved through in vitro fertilization, many molecular mechanisms are activated during the implantation of the embryo in the uterine lining. In these mechanisms, it is of great importance that the immune system is at the appropriate level for pregnancy. A high or low level of NK cells in the uterine lining can negatively affect the implantation of embryos in the uterus. An excess of these cells in the uterine lining can lead to pregnancy losses. It can be recommended for patients who have experienced 2 or more miscarriages or for patients who have not achieved pregnancy despite transferring 4 or more embryos in previous IVF treatments.